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Obesity
Obesity and Headache
Two large studies initially showed a correlation between obesity and chronic daily headache, but not migraine. That means that the more weight you are carrying, the more likely you are to have chronic daily headache. More recent studies, however, do suggest that there may a correlation between migraine and both total body obesity and abdominal obesity.
A BMI (Body Mass Index) of 30 or more places an individual at risk for new onset of chronic daily headaches, which is a condition called New Daily Persistent Headache. A BMI of 25 to 30 is considered “overweight.” A BMI of 30 to 35 is called class I obesity, 35-40 is class II obesity, and BMI over 40 is class III obesity. Most of the studies that determined a correlation between obesity and migraine also did so at a BMI of 30 or greater, although the most risk was seen for class II obese women of reproductive age. Neither the prevalence of migraine nor the risk of severe headache were increased in older women or men with total obesity or abdominal obesity.
There is emerging evidence to suggest that there may be a correlation between metabolic syndrome and migraine as well. An increased waist-to-hip ratio is one of the diagnostic criteria for metabolic syndrome.
Interestingly, there was also an increased rate of headache in the underweight. The best BMI in order to avoid headache is 20. What has not yet been determined is whether there are shared genetic factors that place a given individual at risk for both migraine and obesity, or whether something about migraine and the neurochemical changes that go on in the brain predispose toward obesity.
References:
1. Katsnelson MJ, Peterlin BL, Rosso AL, Alexander GM, Erwin KL. Self-reported vs measured body mass indices in migraineurs. Headache. 2009;49(5):663-668. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19472442
2. Bigal ME, Lipton RB. Putative mechanisms of the relationship between obesity and migraine progression. Curr Pain Headache Rep. 2008;12(3):207-212. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18796271
3. Bigal ME, Lipton RB, Holland PR, Goadsby PJ. Obesity, migraine, and chronic migraine: Possible mechanisms of interaction. Neurology. 2007;68(21):1851-1861. Available at: http://www.neurology.org/cgi/content/abstract/68/21/1851
4. Peterlin BL, Rosso AL, Rapoport AM, Scher AI. Obesity and Migraine: The Effect of Age, Gender and Adipose Tissue Distribution. Headache. 2009. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19496830
5. Bigal ME, Liberman JN, Lipton RB. Obesity and migraine: A population study. Neurology. 2006;66(4):545-550. Available at: http://www.neurology.org/cgi/content/abstract/66/4/545
6. Guldiken B, Guldiken S, Taskiran B, et al. Migraine in metabolic syndrome. Neurologist. 2009;15(2):55-58. Available at: http://www.ncbi.nlm.nih.gov/pubmed/19276782
7. Peterlin BL, Rapoport AM, Kurth T. Migraine and Obesity: Epidemiology, Mechanisms, and Implications. Headache: The Journal of Head and Face Pain. 2009. Available at: http://www3.interscience.wiley.com/cgi-bin/fulltext/122659048/main.html,ftx_abs
8. Ford ES, Li C, Pearson WS, et al. Body mass index and headaches: findings from a national sample of US adults. Cephalalgia. 2008;28(12):1270-1276. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18727641
9. Bigal ME, Tsang A, Loder E, et al. Body mass index and episodic headaches: a population-based study. Arch. Intern. Med. 2007;167(18):1964-1970. Available at: http://www.ncbi.nlm.nih.gov/pubmed/17923596
10. Keith SW, Wang C, Fontaine KR, Cowan CD, Allison DB. BMI and headache among women: results from 11 epidemiologic datasets. Obesity (Silver Spring). 2008;16(2):377-383. Available at: http://www.ncbi.nlm.nih.gov/pubmed/18239647
by Christina Peterson, MD
updated Feb 8, 2010
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