Migraine Quiz


Hypothyroidism and Headache

Hypothyroidism has been found to be associated with chronic daily headache* in both the varieties of chronic migraine and new daily persistent headache. In one study, 30% of individuals with hypothyroidism had developed mild daily headache within 1-2 months of onset of the thyroid disorder. A history of migraine predisposed to the development of headache.

Hashimoto's Disease, an autoimmune form of chronic thyroiditis, has also been associated with increased likelihood of headache.

A study of white matter hyperintensities seen on MRI in migraine found that either hypothyroidism or hyperthyroidism (too low or too high) was associated with these MRI abnormalities.

* This was chronic migraine without any evidence of medication overuse.


1. Moreau T, Manceau E, Giroud‐Baleydier F, Dumas R, Giroud M. Headache in hypothyroidism. Prevalence and outcome under thyroid hormone therapy. Cephalalgia. 1998;18(10):687-689.
2. Trauninger A, Leél-Őssy E, Kamson DO, et al. Risk factors of migraine-related brain white matter hyperintensities: an investigation of 186 patients. J Headache Pain. 2011;12(1):97-103.

by Christina Peterson, MD

updated Nov 14, 2009